Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4937238 | 0.97 | MEN1 (0.40) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL18890497 | 0.97 | MEN1 (0.40) | MEN1KMT2ANPC1GAAMAPT | |
| Hydrochloric Acid SCHEMBL11685389 | 0.95 | MEN1 (0.39) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL4931900 | 0.91 | MEN1 (0.36) | MEN1KMT2ANPC1GAAMAPT | |
| Acetic Acid SCHEMBL8158380 | 0.87 | MEN1 (0.34) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL4938764 | 0.71 | — | — | |
| SCHEMBL9429297 | 0.69 | — | — | |
| SCHEMBL709998 | 0.69 | — | — | |
| SCHEMBL12319503 | 0.68 | KDM4E (0.33) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL17146543 | 0.68 | KDM4E (0.33) | MEN1KMT2ANPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074552-B1 | Process for the preparation of a highly pure phenothiazine compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6433168-B1 | CHEMICAL INTERMEDIATE FOR MEQUITAZINE; ANTIHISTAMINES | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1074552-A2 | Process for the preparation of a highly pure phenothiazine compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |