SCHEMBL7582860

SCHEMBL7582860

[CH2]C[SiH]([SiH3])CCCCCC

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.40
THRB P10828 1/20 0.40
DNM1 Q05193 6/20 0.32
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8384139 0.84 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1482124 0.81 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7582797 0.75
SCHEMBL8382538 0.73 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8383650 0.73 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8380645 0.73 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8380677 0.73 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8380616 0.73
SCHEMBL8385635 0.73 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8384025 0.72 TSHR (0.40) TSHRTHRBALDH1A1LMNASLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872484-B1 ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORP (JP) 2002-10-02 EP disclosed
US-6329027-B1 Chlorobenzene derivatives, liquid-crystal composition, and liquid-crystal display elements CHISSO CORPORATION (JP) 2001-12-11 US disclosed
EP-1010692-A1 LIQUID-CRYSTAL COMPOUNDS HAVING LARGE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT MADE USING THE LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 2000-06-21 EP disclosed
US-5993690-A Organosilicon compound, liquid crystal composition, and liquid-crystal display element CHISSO CORPORATION (JP) 1999-11-30 US disclosed
EP-0959060-A1 CHLOROBENZENE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENTS CHISSO CORPORATION (JP) 1999-11-24 EP disclosed
EP-0872484-A1 ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-10-21 EP disclosed