Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.36 |
| ▸ | ESR1 | P03372 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583008 | 1.00 | ESR2 (0.36) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL8732388 | 0.83 | NPC1 (0.50) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL18866839 | 0.83 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4NPC1 | |
| SCHEMBL8732391 | 0.83 | NPC1 (0.50) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL17549574 | 0.83 | ESR2 (0.49) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL8725097 | 0.81 | ESR2 (0.38) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL8725091 | 0.81 | ESR2 (0.38) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL10862270 | 0.80 | CYP2C9 (0.52) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL11210312 | 0.80 | CYP2C9 (0.52) | ESR2ESR1CYP2C9CYP3A4DGAT1 | |
| SCHEMBL12736282 | 0.80 | EP300 (0.38) | ESR2ESR1CYP2C9CYP3A4DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872484-B1 | ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORP (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-5993690-A | Organosilicon compound, liquid crystal composition, and liquid-crystal display element | CHISSO CORPORATION (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0872484-A1 | ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-10-21 | — | — | EP | disclosed |