Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294766 | 1.00 | ESR1 (0.32) | ESR1MEN1KMT2APGRHDAC11 | |
| SCHEMBL7581879 | 0.93 | — | — | |
| SCHEMBL18294774 | 0.93 | — | — | |
| SCHEMBL7588182 | 0.90 | — | — | |
| SCHEMBL7588267 | 0.89 | MEN1 (0.33) | ESR1MEN1KMT2APGR | |
| SCHEMBL18294772 | 0.89 | MEN1 (0.33) | ESR1MEN1KMT2APGR | |
| SCHEMBL7588589 | 0.89 | — | — | |
| SCHEMBL7589121 | 0.87 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL18294771 | 0.87 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7588172 | 0.87 | MEN1 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183252-B2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-22 | — | — | US | disclosed |