Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 16/20 | 0.45 |
| ▸ | EGFR | P00533 | 9/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824438 | 0.95 | SRC (0.49) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5825463 | 0.86 | SRC (0.55) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5825503 | 0.85 | KDR (0.60) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5825443 | 0.83 | FGFR2 (0.50) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5824642 | 0.83 | KDR (0.56) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5825902 | 0.83 | KDR (0.56) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5825397 | 0.83 | KDR (0.58) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5825266 | 0.82 | KDR (0.53) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5825720 | 0.82 | SRC (0.50) | SRCTGFBR1KDREGFRPDGFRA | |
| SCHEMBL5824944 | 0.82 | SRC (0.47) | SRCTGFBR1KDREGFRPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243582-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-09-25 | — | — | EP | disclosed |