Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585243 | 0.89 | MAPK14 (0.37) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7082270 | 0.85 | MAPK13 (0.53) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7082272 | 0.85 | MAPK13 (0.53) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7079620 | 0.81 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7079618 | 0.81 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7083146 | 0.79 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11GRM4 | |
| SCHEMBL7083149 | 0.79 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11GRM4 | |
| SCHEMBL7080598 | 0.78 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7080621 | 0.78 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7076539 | 0.74 | MAPK13 (0.64) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |