Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825244 | 0.84 | CYP3A4 (0.68) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL31680519 | 0.82 | CYP3A4 (1.00) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL6680554 | 0.82 | MEN1 (0.71) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL3435311 | 0.82 | CYP3A4 (0.66) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL1322530 | 0.82 | CYP3A4 (1.00) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL2549717 | 0.80 | MEN1 (0.73) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL9235862 | 0.78 | SCN2A (0.68) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL11864526 | 0.77 | CYP3A4 (0.59) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL3842952 | 0.77 | CYP3A4 (0.59) | CYP3A4NFKB1PMP22MEN1KMT2A | |
| SCHEMBL3843730 | 0.75 | CYP3A4 (0.57) | CYP3A4NFKB1PMP22MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |