Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374751 | 0.88 | TACR1 (0.49) | TACR1CYP2D6CFTRKCNH2HTR1A | |
| SCHEMBL27366479 | 0.88 | TACR1 (0.49) | TACR1CYP2D6CFTRKCNH2HTR1A | |
| SCHEMBL27461972 | 0.83 | TACR1 (0.42) | TACR1CYP2D6CFTRKCNH2HTR1A | |
| SCHEMBL7864421 | 0.83 | TACR1 (0.40) | TACR1CYP2D6CFTRKCNH2HTR1A | |
| SCHEMBL6931695 | 0.80 | TACR1 (0.52) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL4913542 | 0.80 | TACR1 (0.52) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL6700500 | 0.80 | TACR1 (0.52) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL6154253 | 0.80 | TACR1 (0.39) | TACR1CYP2D6CFTRKCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL4913478 | 0.79 | TACR1 (0.53) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8539639 | 0.79 | TACR1 (0.45) | TACR1CYP2D6CFTRHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780375-B1 | 3-((5-substituted benzyl)amino)-2-phenylpiperidines as substance p antagonists | PFIZER (US) | 2002-09-11 | — | — | EP | claimed |