Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 8/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.57 |
| ▸ | PTGIR | P43119 | 6/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | PTGFR | P43088 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172727 | 1.00 | PTGER2 (0.57) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7171732 | 0.81 | PTGIR (0.77) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL29799019 | 0.81 | PTGIR (0.77) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7588719 | 0.81 | PTGER2 (0.59) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL23352912 | 0.81 | PTGIR (0.77) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL23352995 | 0.81 | PTGIR (0.77) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7176984 | 0.81 | PTGIR (0.77) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL23352556 | 0.81 | PTGIR (0.77) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL7168139 | 0.81 | PTGER2 (0.59) | PTGER2PTGER3PTGIRPTGER4NR1I2 | |
| SCHEMBL16374815 | 0.81 | PTGIR (0.77) | PTGER2PTGER3PTGIRPTGER4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | claimed |