SCHEMBL7585280

SCHEMBL7585280

CCCCOCCOC(C)C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 1/20 0.35
EPHX2 P34913 1/20 0.35
HSD17B10 Q99714 1/20 0.34
SPHK1 Q9NYA1 1/20 0.33
USP2 O75604 1/20 0.33
RARB P10826 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3419111 1.00 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL4838940 1.00 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL20825331 1.00 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL4840053 0.93 HTT (0.52) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL27888500 0.93 HTT (0.52) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL24754956 0.91 HTT (0.56) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL18510366 0.91 HTT (0.56) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL18510372 0.91 HTT (0.56) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL20206377 0.91 HTT (0.56) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL25341871 0.91 HTT (0.56) TSHRCYP3A4MAPTMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082936-B Blocked polyisocyanate composition and method for producing same, resin composition, resin film and method for producing same, and laminate 旭化成株式会社 2024-04-05 CN disclosed
EP-3689936-B1 BLOCKED POLYISOCYANATE COMPOSITION AND USE THEREOF ASAHI CHEMICAL IND (JP) 2024-03-06 EP disclosed
CN-117580887-A Blocked polyisocyanate composition, resin film, and laminate 旭化成株式会社 2024-02-20 CN disclosed
CN-113939552-B Blocked polyisocyanate composition, one-component coating composition, coating film and coated article 旭化成株式会社 2024-01-30 CN disclosed
US-20230331737-A1 MTORC1 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. 2023-10-19 US disclosed
US-11661473-B2 Blocked polyisocyanate composition and use thereof ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-05-30 US disclosed
CN-114174483-B Working medium for refrigerant compression refrigeration cycle device and refrigeration cycle device 青木油脂工業株式会社 2023-05-09 CN disclosed
CN-116082936-A Blocked polyisocyanate composition and method for producing same, resin composition, resin film and method for producing same, and laminate 旭化成株式会社 2023-05-09 CN disclosed
CN-115667350-A Blocked polyisocyanate composition, resin film, and laminate 旭化成株式会社 2023-01-31 CN disclosed
CN-111556795-B Coating method and coating film 旭化成株式会社 2022-11-08 CN disclosed
CN-1320073-C Composition for forming silica based coating film, silica based coating film and method for preparation thereof, and electronic parts HITACHI CHEMICAL CO LTD (JP) 2007-06-06 CN disclosed
CN-1950473-A Insulating film forming composition, preparing method thereof, silica dioxide insulating film and preparing method thereof JSR CORP (JP) 2007-04-18 CN disclosed
CN-1769349-A Composition for forming silica based coating film, silica based coating film and method for preparation thereof, and electronic parts HITACHI CHEMICAL CO LTD (JP) 2006-05-10 CN disclosed
CN-1637097-A Composition for forming silica based coating film, silica based coating film and method for preparation thereof, and electronic parts HITACHI CHEMICAL CO LTD (JP) 2005-07-13 CN disclosed
CN-1639283-A Composition for forming silica coating film, silica coating film and method for producing same, and electronic component HITACHI CHEMICAL CO LTD (JP) 2005-07-13 CN disclosed
CN-1531031-A Composition for shaping porous membrane, porous membrane and shaping method thereof, interlayer insulative membrane and semiconductor device 信越化学工业株式会社 2004-09-22 CN disclosed
CN-1163476-C Biuret polyisocyanic acid ester and its producing process 旭化成株式会社 2004-08-25 CN disclosed
CN-1335302-A Biuret polyisocyanic acid ester and its producing process ASAHI CHEMICAL IND (JP) 2002-02-13 CN disclosed
US-20020012787-A1 COATING MATERIAL FOR INFORMATION DISPLAY SURFACE AND DISPLAY MEDIUM IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-01-31 US disclosed
US-4176132-A Reaction of organic diisocyanates with water ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331737-A1 MTORC1 MODULATORS AND USES THEREOF MTOR, RPTOR, RICTOR TSHR 2893/4885CYP3A4 4767/4885MAPT 1500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.