Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689788 | 0.78 | EGLN1 (0.41) | ALDH1A1GAASMN1; SMN2TSHRLMNA | |
| SCHEMBL6320653 | 0.77 | HCAR2 (0.36) | HCAR2ALDH1A1TSHRLMNAESR1 | |
| SCHEMBL11767879 | 0.77 | EGLN1 (0.39) | ALDH1A1GAASMN1; SMN2TSHRLMNA | |
| SCHEMBL7575941 | 0.75 | GAA (0.38) | HCAR2ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL9513524 | 0.75 | HCAR2 (0.35) | HCAR2ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL6588379 | 0.75 | — | — | |
| SCHEMBL138475 | 0.74 | HCAR2 (0.48) | HCAR2ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL22591380 | 0.73 | — | — | |
| Water SCHEMBL27557216 | 0.71 | HCAR2 (0.46) | HCAR2ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL19978742 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588372-B1 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL IND CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0357792-B1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL IND CO LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0588372-A1 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5252739-A | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5175300-A | Reacting a halo-oxalactic ester with 2-propenal and ammonia; cyclization | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1992-12-29 | — | — | US | disclosed |