Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 16/20 | 0.48 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425323 | 0.85 | HTR2A (0.53) | HTR2AHTR6OXER1SCN9A | |
| SCHEMBL6426061 | 0.85 | HTR2A (0.53) | HTR2AHTR6OXER1SCN9ALMNA | |
| SCHEMBL27721427 | 0.84 | HTR2A (0.58) | HTR2AHTR6OXER1SCN9A | |
| SCHEMBL2824959 | 0.84 | OXER1 (0.58) | HTR2AHTR6OXER1SCN9A | |
| SCHEMBL5304010 | 0.83 | HTR2A (0.57) | HTR2AHTR6OXER1SCN9A | |
| SCHEMBL627039 | 0.83 | HTR2A (0.57) | HTR2AHTR6OXER1SCN9A | |
| SCHEMBL27487257 | 0.82 | HTR2A (0.53) | HTR2AHTR6OXER1SCN9A | |
| SCHEMBL29424269 | 0.82 | HTR2A (0.59) | HTR2AHTR6OXER1SCN9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8648129 | 0.82 | HTR2A (0.55) | HTR2AHTR6OXER1SCN9A | |
| SCHEMBL7528710 | 0.82 | HTR2A (0.59) | HTR2AHTR6OXER1SCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212056-A1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001012185-A1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-02-22 | — | — | WO | disclosed |