Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779362 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7542107 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29263645 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7548208 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7548687 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29256400 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7542052 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8779372 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9847185 | 1.00 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28908599 | 0.94 | KMT2A (0.70) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208451-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | ADDA BIOTECH INC. | 2021-12-28 | — | — | US | disclosed |
| US-10472404-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | ADDA BIOTECH INC. (CN) | 2019-11-12 | — | — | US | disclosed |
| EP-2851429-B1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | ADDA BIOTECH INC (CN) | 2019-07-24 | — | — | EP | disclosed |
| CN-107739409-A | Albumen, protein conjugate and its application for treating diabetes | 爱德迪安（北京）生物技术有限公司 | 2018-02-27 | — | — | CN | disclosed |
| CN-104302772-B | Protein for diabetes treatment, protein conjugate and application thereof | 爱德迪安（北京）生物技术有限公司 | 2017-11-10 | — | — | CN | disclosed |
| US-9745359-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | ADDA BIOTECH INC. (CN) | 2017-08-29 | — | — | US | disclosed |
| US-20170233447-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | ADDA BIOTECH INC. (CN) | 2017-08-17 | — | — | US | disclosed |
| US-20150183847-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | ADDA BIOTECH INC. (CN) | 2015-07-02 | — | — | US | disclosed |
| EP-2851429-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | Adda Biotech Inc. (CN) | 2015-03-25 | — | — | EP | disclosed |
| CN-104302772-A | Protein for diabetes treatment, protein conjugate and application thereof | ADDA BIOTECH INC | 2015-01-21 | — | — | CN | disclosed |
| WO-2013170636-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | 爱德迪安（北京）生物技术有限公司 (CN) | 2013-11-21 | — | — | WO | disclosed |
| EP-0885886-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN SEIFUN GROUP INC (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5972943-A | N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0885886-A1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0507348-B1 | Superoxide dismutase derivatives | KURARAY CO (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5360914-A | Intermediates for superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5238837-A | Antiinflammatory agents, antiulcer agents | KURARAY CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0507348-A2 | Superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208451-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | GLP1R, GIPR, IAPP | HDAC8 3799/4885HDAC3 3021/4885HDAC4 4053/4885 |
| US-10472404-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | GLP1R, GIPR, IAPP | HDAC8 3799/4885HDAC3 3021/4885HDAC4 4053/4885 |
| US-20150183847-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | GLP1R, GIPR, IAPP | HDAC8 3853/4885HDAC3 3120/4885HDAC4 4117/4885 |
| US-20170233447-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | GLP1R, GIPR, IAPP | HDAC8 3799/4885HDAC3 3021/4885HDAC4 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.