Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | FNTA | P49354 | 5/20 | 0.58 |
| ▸ | FNTB | P49356 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | SQLE | Q14534 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563416 | 1.00 | KMT2A (0.59) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL1155187 | 1.00 | KMT2A (0.59) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL1155126 | 1.00 | KMT2A (0.59) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL7586419 | 1.00 | KMT2A (0.59) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL3018424 | 0.92 | KDM4E (0.52) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL16428263 | 0.89 | FNTA (0.57) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL16428261 | 0.89 | FNTA (0.57) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL5703340 | 0.87 | FNTA (0.48) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL16428593 | 0.87 | FNTA (0.54) | KMT2AFNTAFNTBKDM4EATM | |
| SCHEMBL16428591 | 0.87 | FNTA (0.54) | KMT2AFNTAFNTBKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |