SCHEMBL7586541

SCHEMBL7586541

Cc1nc(S(C)(=O)=O)ncc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.55
TP53 P04637 11/20 0.55
TLR9 Q9NR96 9/20 0.55
NPC1 O15118 7/20 0.55
ALDH1A1 P00352 4/20 0.55
NPSR1 Q6W5P4 4/20 0.55
HTT P42858 3/20 0.55
XBP1 P17861 3/20 0.55
MAPK1 P28482 2/20 0.55
HSD17B10 Q99714 1/20 0.55
LMNA P02545 5/20 0.46
SMN1; SMN2 Q16637 6/20 0.43
RAB9A P51151 5/20 0.43
MITF O75030 2/20 0.43
S1PR4 O95977 2/20 0.43
PAX8 Q06710 2/20 0.43
PKM P14618 1/20 0.43
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
AGTR1 P30556 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3631289 0.83 MAPT (0.51) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL9627295 0.82 TP53 (0.50) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL27638332 0.80 NPC1 (0.52) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL2350715 0.78 MAPT (0.42) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL22489959 0.78 TP53 (0.46) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL5416222 0.77 LRRK2 (0.51) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL27392493 0.77 MAPT (0.54) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL2475444 0.76 TP53 (0.64) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL10582722 0.75 TP53 (0.41) MAPTTP53TLR9NPC1ALDH1A1
SCHEMBL15286672 0.74 MAPT (0.62) MAPTTP53TLR9NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669381-B1 Dye, ink containing the same, and ink-jet recording method and instrument using the ink CANON KK (JP) 2002-09-11 EP claimed
US-5733363-A WATER FASTNESS; SOLUTION SOLUBILITY CANON KABUSHIKI KAISHA (JP) 1998-03-31 US claimed
EP-0669381-A2 Dye, ink containing the same, and ink-jet recording method and instrument using the ink CANON KABUSHIKI KAISHA (JP) 1995-08-30 EP claimed
JP-57174360-A None JP disclosed
CN-1085280-A The manufacture method of modified form fibrous material and colouring method thereof HOECHST AG (DE) 1994-04-13 CN disclosed
US-4544738-A FIBER-REACTIVE YELLOW AND ORANGE DYES BASF AKTIENGESELLSCHAFT (DE) 1985-10-01 US disclosed
JP-S57174360-A INK COMPOSITION NIPPON TELEGR & TELEPH CORP <NTT> 1982-10-27 JP disclosed
US-4172736-A CARBOXYETHYL GUAR HENKEL CORPORATION (US) 1979-10-30 US disclosed