⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910847 | 0.75 | — | — | |
| SCHEMBL8081840 | 0.73 | — | — | |
| SCHEMBL386210 | 0.73 | — | — | |
| SCHEMBL8996097 | 0.73 | — | — | |
| SCHEMBL11201987 | 0.72 | — | — | |
| SCHEMBL28192681 | 0.72 | — | — | |
| SCHEMBL5636210 | 0.71 | — | — | |
| SCHEMBL114805 | 0.71 | — | — | |
| SCHEMBL20578982 | 0.71 | — | — | |
| SCHEMBL9853359 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180237397-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2018-08-23 | — | — | US | claimed |
| US-9776972-B2 | Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof | EPIZYME INC. (US) | 2017-10-03 | — | — | US | claimed |
| US-9346761-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-05-24 | — | — | US | claimed |
| US-20160137609-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-05-19 | — | — | US | claimed |
| US-20140323537-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-10-30 | — | — | US | claimed |
| US-5730966-A | WATER OR ALCOHOL SOLUBLE OR DISPERSIBLE COPOLYMER FOR STYLING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-24 | — | — | US | claimed |
| EP-0571593-B1 | NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM | INVEST JUSTESA IMAGEN S A CENT (ES) | 1996-10-30 | — | — | EP | claimed |
| US-4873263-A | ESTER PRODRUG DERIVATIVES | MERCK & CO., INC. (US) | 1989-10-10 | — | — | US | claimed |
| US-4771073-A | ESTER PRODRUG DERIVATIVES OF L-DOPA, OPTIONALLY WITH A DECARBOXYLASE INHIBITOR | MERCK & CO., INC. (US) | 1988-09-13 | — | — | US | claimed |
| CN-114805367-B | Triazole pyrimidine derivative and preparation method and application thereof | 郑州大学 | 2023-04-07 | — | — | CN | disclosed |
| EP-1246897-A1 | PHOTOCATALYTIC COMPOSITIONS AND METHODS | Reckitt Benckiser (UK) LIMITED (GB) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001046367-A1 | PHOTOCATALYTIC COMPOSITIONS AND METHODS | RECKITT BENCKISER (UK) LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |
| EP-0571593-B1 | NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM | INVEST JUSTESA IMAGEN S A CENT (ES) | 1996-10-30 | — | — | EP | disclosed |
| EP-0105590-A1 | Process for the production of guanidinoheterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-04-18 | — | — | EP | disclosed |