Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | CCKAR | P32238 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590610 | 1.00 | KDM4E (0.53) | KDM4ELMNAALDH1A1CNR2PTGDR2 | |
| SCHEMBL27989288 | 0.90 | KDM4E (0.59) | KDM4ELMNAALDH1A1PTGDR2TBXA2R | |
| Hydrochloric Acid SCHEMBL27883098 | 0.89 | KDM4E (0.61) | KDM4ELMNAALDH1A1PTGDR2TBXA2R | |
| Bromide SCHEMBL2430564 | 0.89 | KDM4E (0.58) | KDM4ELMNAALDH1A1PTGDR2TBXA2R | |
| SCHEMBL7413263 | 0.87 | PTGDR2 (0.56) | KDM4ELMNAALDH1A1CNR2PTGDR2 | |
| Hydrochloric Acid SCHEMBL7412317 | 0.86 | PTGDR2 (0.55) | KDM4ELMNAALDH1A1CNR2PTGDR2 | |
| SCHEMBL13273561 | 0.84 | KDM4E (0.67) | KDM4EALDH1A1PTGDR2TBXA2RPTGDR | |
| SCHEMBL16559078 | 0.84 | KDM4E (0.67) | KDM4EALDH1A1PTGDR2TBXA2RPTGDR | |
| SCHEMBL13677407 | 0.81 | PTGDR2 (0.52) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| SCHEMBL7591129 | 0.81 | PTGDR2 (0.49) | KDM4ELMNAALDH1A1CNR2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728743-B1 | 3-Amino-tetrahydrocarbazol propanoic acid esters | BAYER AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| EP-0728743-A1 | 3-Amino-tetrahydrocarbazol propanoic acid esters | BAYER AG (DE) | 1996-08-28 | — | — | EP | disclosed |