Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7586755

CC1(C)CCC[Si](c2ccccc2)(c2ccccc2)O1.N.N

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182249 0.98
SCHEMBL17721898 0.96
Phenol SCHEMBL28164325 0.90 CA12 (0.34)
SCHEMBL3263249 0.79
SCHEMBL15355529 0.77 SLC18A3 (0.30)
SCHEMBL29035536 0.77
SCHEMBL27994036 0.76 SMN1; SMN2 (0.31)
SCHEMBL7107826 0.76
SCHEMBL2352430 0.75 AKR1C1 (0.35)
SCHEMBL28912813 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0822951-B1 POLYDIORGANOSILOXANE POLYUREA SEGMENTED COPOLYMERS AND A PROCESS FOR MAKING SAME MINNESOTA MINING & MFG (US) 2002-09-04 EP disclosed
US-6355759-B1 CONTINUOUSLY REACTING POLYISOCYANATE, POLYDIORGANOSILOXANE DIAMINE AND/OR POLYAMINE; CONVEYING, EXTRUSION; HARD AND SOFT SEGMENTS; SOLVENT INSOLUBILITY; COPOLYMERIZATION, CONDENSATION POLYMERIZATION 3M INNOVATIVE PROPERTIES COMPANY 2002-03-12 US disclosed
EP-0822951-A1 POLYDIORGANOSILOXANE POLYUREA SEGMENTED COPOLYMERS AND A PROCESS FOR MAKING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-02-11 EP disclosed
WO-1996034029-A1 POLYDIORGANOSILOXANE POLYUREA SEGMENTED COPOLYMERS AND A PROCESS FOR MAKING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-10-31 WO disclosed