Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL112916 | 1.00 | — | — | |
| Glycine SCHEMBL30785089 | 1.00 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL27784221 | 1.00 | — | — | |
| Glycine SCHEMBL28342088 | 1.00 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL15542628 | 0.96 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL8991350 | 0.96 | — | — | |
| Glycine SCHEMBL15542050 | 0.96 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL8069599 | 0.96 | — | — | |
| Glycine SCHEMBL15541784 | 0.96 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL9474283 | 0.96 | GLRA1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848714-B1 | METHOD FOR MANUFACTURING COBALT CATALYSTS | PROCTER & GAMBLE (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-0832088-B1 | METHOD FOR MANUFACTURING COBALT CATALYSTS | PROCTER & GAMBLE (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0848714-A1 | METHOD FOR MANUFACTURING COBALT CATALYSTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-24 | — | — | EP | disclosed |
| EP-0832088-A1 | METHOD FOR MANUFACTURING COBALT CATALYSTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997005153-A1 | METHOD FOR MANUFACTURING COBALT CATALYSTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-02-13 | — | — | WO | disclosed |
| US-5597936-A | Method for manufacturing cobalt catalysts | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1997000263-A1 | METHOD FOR MANUFACTURING COBALT CATALYSTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |
| US-5559261-A | Method for manufacturing cobalt catalysts | THE PROCTER & GAMBLE COMPANY (US) | 1996-09-24 | — | — | US | disclosed |