SCHEMBL7586888

SCHEMBL7586888

Cc1ccc(C(N)=O)c(Cl)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 3/20 0.49
KMT2A Q03164 3/20 0.42
ATM Q13315 1/20 0.42
SIRT3 Q9NTG7 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 3/20 0.39
NNMT P40261 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
POLB P06746 1/20 0.37
LMNA P02545 1/20 0.37
MKNK1 Q9BUB5 1/20 0.37
MKNK2 Q9HBH9 1/20 0.37
TTR P02766 2/20 0.36
MEN1 O00255 1/20 0.36
AKR1B10 O60218 1/20 0.36
ABCB11 O95342 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811777 0.86 KMT2A (0.52) KMT2AATMALDH1A1KDM4EGLA
SCHEMBL10407716 0.85 CLCN2 (0.44) CLCN2KMT2AATMSIRT3TDP1
SCHEMBL28942795 0.85 CLCN2 (0.47) CLCN2KMT2AATMSIRT3TDP1
SCHEMBL2466290 0.81 CLCN2 (0.51) CLCN2KMT2AATMSIRT3TDP1
SCHEMBL109811 0.80 CLCN2 (0.49) CLCN2KMT2AALDH1A1KDM4ETTR
SCHEMBL107481 0.80 CLCN2 (0.38) CLCN2KMT2AALDH1A1GAALMNA
SCHEMBL11214195 0.80 CLCN2 (0.38) CLCN2KMT2AATMALDH1A1GAA
Hydrochloric Acid SCHEMBL28796608 0.79 CLCN2 (0.50) CLCN2KMT2AATMSIRT3TDP1
SCHEMBL30862084 0.79 CLCN2 (0.43) CLCN2KMT2AATMSIRT3TDP1
SCHEMBL3121452 0.77 KMT2A (0.55) CLCN2KMT2AATMALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1247450-A2 Fungicidal composition containing an N-Acetonylbenzamide and a copper containing fungicide Dow AgroSciences LLC (US) 2002-10-09 EP claimed
EP-0946093-A2 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO S.p.A. (IT) 1999-10-06 EP claimed
WO-1998026654-A2 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO S.P.A. (IT) 1998-06-25 WO claimed
EP-0946093-A2 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO S.p.A. (IT) 1999-10-06 EP disclosed
WO-1998026654-A2 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO S.P.A. (IT) 1998-06-25 WO disclosed