Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 5/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411678 | 0.83 | SMPD1 (0.41) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL393229 | 0.80 | SMPD1 (0.39) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL5908917 | 0.71 | SMPD1 (0.47) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL5908847 | 0.71 | SMPD1 (0.47) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL5908958 | 0.70 | SMPD1 (0.50) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL1923665 | 0.69 | SMPD1 (0.46) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL1923635 | 0.69 | SMPD1 (0.48) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL5964459 | 0.69 | SMPD1 (0.48) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL5014661 | 0.68 | SMPD1 (0.44) | SMPD1FDPSLPAR3LPAR1LPAR2 | |
| SCHEMBL7006858 | 0.68 | SMPD1 (0.41) | SMPD1FDPSLPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197986-B1 | PHOSPHATO- OR PHOSPHONOALKYLSILANEDIOLS, TRIOLS; DRUGS, COSMETICS | EXSYMOL S.A.M. (FR) | 2001-03-06 | — | — | US | claimed |
| EP-0867445-B1 | Complexes based on biologically silicon in solid form. | EXSYMOL SA (MC) | 2002-10-09 | — | — | EP | disclosed |
| US-6197986-B1 | PHOSPHATO- OR PHOSPHONOALKYLSILANEDIOLS, TRIOLS; DRUGS, COSMETICS | EXSYMOL S.A.M. (FR) | 2001-03-06 | — | — | US | disclosed |
| EP-0867445-A1 | Compounds based on biologically active silicon in solid form | EXSYMOL S.A.M. (MC) | 1998-09-30 | — | — | EP | disclosed |