Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613337 | 1.00 | TUBB1 (0.62) | TUBB1MCL1FGFR1CYP1A1CYP1A2 | |
| SCHEMBL7188936 | 0.86 | MEN1 (0.67) | TUBB1MCL1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7188944 | 0.86 | MEN1 (0.67) | TUBB1MCL1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7550612 | 0.82 | ABCG2 (0.76) | FGFR1MAPK1MAPTMEN1USP2 | |
| SCHEMBL7550618 | 0.82 | ABCG2 (0.76) | FGFR1MAPK1MAPTMEN1USP2 | |
| SCHEMBL10824463 | 0.82 | TUBB1 (0.76) | TUBB1MCL1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL15304531 | 0.82 | TUBB1 (0.71) | TUBB1MCL1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL10824465 | 0.82 | TUBB1 (0.76) | TUBB1MCL1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL15756404 | 0.81 | TUBB1 (0.64) | TUBB1MCL1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL15756405 | 0.81 | TUBB1 (0.64) | TUBB1MCL1CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020143064-A1 | Novel use of compounds of the chalcones class | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | US | claimed |
| US-20020143064-A1 | Novel use of compounds of the chalcones class | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | US | disclosed |
| WO-2002047604-A2 | NOVEL USE OF CHALCONE CLASS COMPOUNDS FOR INHIBITING TUMORAL MASS VASCULARIZATION | AVENTIS PHARMA S.A. (FR) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143064-A1 | Novel use of compounds of the chalcones class | NR2E1, FLT1, KDR | TUBB1 304/4885MCL1 764/4885FGFR1 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.