SCHEMBL7587494

SCHEMBL7587494

OC1(O)CCCC1(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.42
AKR1C1 Q04828 1/20 0.42
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
OPRM1 P35372 3/20 0.38
OPRK1 P41145 2/20 0.38
OPRL1 P41146 2/20 0.38
HDAC4 P56524 2/20 0.37
HSD11B1 P28845 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170242 0.95 DPP4 (0.47) DPP4AKR1C1MAOAMAOBTAAR1
SCHEMBL1955879 0.93 DPP4 (0.45) DPP4AKR1C1OPRM1HDAC4
SCHEMBL1958979 0.93 DPP4 (0.45) DPP4AKR1C1OPRM1HDAC4
SCHEMBL1958751 0.93 DPP4 (0.45) DPP4AKR1C1OPRM1HDAC4
SCHEMBL1958571 0.93 DPP4 (0.45) DPP4AKR1C1OPRM1HDAC4
SCHEMBL1954905 0.93 DPP4 (0.45) DPP4AKR1C1OPRM1HDAC4
SCHEMBL12276559 0.93 DPP4 (0.45) DPP4AKR1C1OPRM1HDAC4
SCHEMBL753111 0.83 DPP4 (0.44) DPP4AKR1C1MAOAMAOBTAAR1
SCHEMBL11582057 0.79 AKR1C1 (0.43) DPP4AKR1C1MAOAMAOBTAAR1
SCHEMBL29266776 0.76 DPP4 (0.40) DPP4AKR1C1MAOAMAOBTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915921-B1 CROSS-LINKING AGENTS FOR EMULSION POLYMERS BASF AG (DE) 2002-10-02 EP disclosed
EP-0915920-B1 IMPACT RESISTANT THERMOPLASTIC MOULDING MATERIALS BASF AG (DE) 2001-09-19 EP disclosed
US-6197872-B1 CORE-SHELL EMULSION POLYMER BASF AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed
US-6103821-A POLYMERIZING A CROSS-LINKED PARTICULATE EMULSION POLYMER IN PRESENCE OF A CURING AGENT CONSISTING OF A HOMO- OR CO-ADDITION POLYMER BASF AKTIENGESELLSCHAFT (DE) 2000-08-15 US disclosed
EP-0915920-A1 IMPACT RESISTANT THERMOPLASTIC MOULDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1999-05-19 EP disclosed
EP-0915921-A1 CROSS-LINKING AGENTS FOR EMULSION POLYMERS BASF AKTIENGESELLSCHAFT (DE) 1999-05-19 EP disclosed
WO-1998005694-A1 IMPACT RESISTANT THERMOPLASTIC MOULDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1998-02-12 WO disclosed
WO-1998005695-A1 CROSS-LINKING AGENTS FOR EMULSION POLYMERS BASF AKTIENGESELLSCHAFT (DE) 1998-02-12 WO disclosed