Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.63 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.54 |
| ▸ | PTGFR | P43088 | 2/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169600 | 0.91 | PTGIR (0.71) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL7168396 | 0.91 | PTGIR (0.63) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL8079366 | 0.91 | PTGIR (0.71) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL7177032 | 0.90 | PTGIR (0.70) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL23352995 | 0.90 | PTGIR (0.77) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL29799019 | 0.90 | PTGIR (0.77) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL23352556 | 0.90 | PTGIR (0.77) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL7176984 | 0.90 | PTGIR (0.77) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL7171732 | 0.90 | PTGIR (0.77) | PTGIRPTGER2PTGER4PTGER3PTGFR | |
| SCHEMBL23352912 | 0.90 | PTGIR (0.77) | PTGIRPTGER2PTGER4PTGER3PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | claimed |
| US-6110969-A | Cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO. LTD. (JP) | 2000-08-29 | — | — | US | claimed |
| EP-0860430-A2 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | claimed |
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6110969-A | Cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO. LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0860430-A2 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |