SCHEMBL7588136

SCHEMBL7588136

CCCCCC(C)(C)c1cc(-c2cc(C(C)(C)CCCCC)cc(-n3nc4ccccc4n3)c2O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 16/20 0.44
CNR2 P34972 15/20 0.44
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
GPR18 Q14330 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7592856 0.93 CNR1 (0.47) CNR1CNR2NPC1RAB9ALMNA
SCHEMBL2464792 0.90 CNR2 (0.44) CNR1CNR2NPC1RAB9ALMNA
SCHEMBL2467398 0.89 CNR2 (0.46) CNR1CNR2NPC1RAB9ALMNA
SCHEMBL673359 0.89 CNR1 (0.40) CNR1CNR2NPC1RAB9ALMNA
SCHEMBL258641 0.88 CNR1 (0.41) CNR1CNR2NPC1RAB9ALMNA
SCHEMBL139856 0.88 CNR1 (0.47) CNR1CNR2NPC1RAB9ALMNA
SCHEMBL22289027 0.88 CNR1 (0.42) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL9408867 0.86 CNR2 (0.42) CNR1CNR2NPC1RAB9ALMNA
SCHEMBL5643806 0.86 CNR2 (0.41) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL13370057 0.85 CNR1 (0.38) CNR1CNR2NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344505-B1 Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers CYTEC INDUSTRIES INC. 2002-02-05 US claimed
EP-1238003-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2002-09-11 EP disclosed
US-6344505-B1 Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers CYTEC INDUSTRIES INC. 2002-02-05 US disclosed
US-6344505-B1 Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers CYTEC INDUSTRIES INC. 2002-02-05 US disclosed
WO-2001034694-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2001-05-17 WO disclosed