Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570961 | 0.91 | HPRT1 (0.46) | HPRT1KMT2AMEN1LMNATSHR | |
| SCHEMBL7571914 | 0.83 | HPRT1 (0.49) | HPRT1KMT2AMEN1TSHR | |
| SCHEMBL7982326 | 0.83 | HPRT1 (0.51) | HPRT1 | |
| SCHEMBL7570074 | 0.83 | HPRT1 (0.53) | HPRT1KMT2ALMNAHTT | |
| SCHEMBL7575108 | 0.83 | HPRT1 (0.53) | HPRT1 | |
| SCHEMBL7570980 | 0.82 | HPRT1 (0.48) | HPRT1KMT2AMEN1LMNATSHR | |
| SCHEMBL7570941 | 0.81 | HPRT1 (0.49) | HPRT1 | |
| SCHEMBL7572274 | 0.81 | HPRT1 (0.49) | HPRT1 | |
| SCHEMBL7576799 | 0.81 | HPRT1 (0.51) | HPRT1KMT2AMEN1LMNA | |
| SCHEMBL7567089 | 0.80 | HPRT1 (0.54) | HPRT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237890-A1 | SYNTHESIS AND METHODS OF USE OF 9-SUBSTITUTED GUANINE DERIVATIVES | Neotherapeutics, Inc. (US) | 2002-09-11 | — | — | EP | claimed |
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | claimed |
| WO-2001029039-A1 | SYNTHESIS AND METHODS OF USE OF 9-SUBSTITUTED GUANINE DERIVATIVES | NEOTHERAPEUTICS, INC. (US) | 2001-04-26 | — | — | WO | claimed |