Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.77 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.77 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.67 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.51 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.51 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCB | P05771 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458233 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL10896195 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL29353224 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL2813163 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL496845 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL2814732 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL5055004 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL31198159 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL31439420 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL30443866 | 0.87 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702556-B1 | (PHOSPHO)LIPIDS FOR COMBATTING HEPATITIS B VIRUS INFECTION | UNIV WAKE FOREST (US) | 2002-10-23 | — | — | EP | disclosed |
| US-6030960-A | INHIBITING THE PRODUCTION OF HEPATITIS VIRUS-INDUCED ANTIGENS IN A HUMAN SUBJECT BY ADMINISTERING A COMPOUND | WAKE FOREST UNIVERSITY (US) | 2000-02-29 | — | — | US | disclosed |
| US-5770584-A | ADMINISTERING AN ALKYL LIPID OR ALKYL LIPID DERIVATIVE VIRICIDES | WAKE FOREST UNIVERSITY (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0702556-A1 | (PHOSPHO)LIPIDS FOR COMBATTING HEPATITIS B VIRUS INFECTION | WAKE FOREST UNIVERSITY (US) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994028908-A2 | (PHOSPHO)LIPIDS FOR COMBATTING HEPATITIS B VIRUS INFECTION | WAKE FOREST UNIVERSITY (US) | 1994-12-22 | — | — | WO | disclosed |