Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632411 | 0.87 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL4630657 | 0.86 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL27491258 | 0.85 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL4632363 | 0.85 | EDNRA (0.82) | EDNRAEDNRB | |
| SCHEMBL4631353 | 0.84 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL4631405 | 0.84 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL6588138 | 0.83 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL27508438 | 0.83 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL4630639 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6150988 | 0.82 | EDNRA (0.84) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980369-A1 | SULFONAMIDES FOR TREATMENT OF ENDOTHELIN-MEDIATED DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049162-A1 | SULFONAMIDES FOR TREATMENT OF ENDOTHELIN-MEDIATED DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |