Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 17/20 | 0.62 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103389 | 0.84 | LCK (0.79) | LCKMKNK1MKNK2 | |
| SCHEMBL7590572 | 0.78 | LCK (0.52) | LCKMKNK1MKNK2 | |
| SCHEMBL7987452 | 0.78 | LCK (0.80) | LCK | |
| SCHEMBL7503909 | 0.77 | LCK (0.45) | LCKMKNK1MKNK2 | |
| SCHEMBL7592779 | 0.77 | LCK (1.00) | LCKMKNK1MKNK2 | |
| SCHEMBL7016875 | 0.77 | LCK (1.00) | LCKMKNK1MKNK2 | |
| SCHEMBL7586925 | 0.75 | LCK (0.81) | LCK | |
| SCHEMBL7569953 | 0.75 | LCK (0.81) | LCK | |
| SCHEMBL7019359 | 0.73 | LCK (1.00) | LCKMKNK1MKNK2 | |
| SCHEMBL7019366 | 0.73 | LCK (1.00) | LCKMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206260-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1206260-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6329380-B1 | PYRIMIDINE BENZIMIDIZAZOLE, PYRIMIDINEIMIDAZOLE OR PYRIDINE IMIDAZOLE COMPOUNDS FOR ANTICANCER AGENTS OR ATHEROSCLEROSIS | MERCK & CO., INC. | 2001-12-11 | — | — | US | disclosed |
| WO-2001000207-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |