Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873240 | 1.00 | LCK (0.58) | LCKIDH1 | |
| SCHEMBL7596940 | 0.90 | LCK (0.69) | LCK | |
| SCHEMBL7543704 | 0.90 | LCK (0.69) | LCK | |
| SCHEMBL7596936 | 0.90 | LCK (0.69) | LCK | |
| SCHEMBL7867885 | 0.90 | LCK (0.69) | LCK | |
| SCHEMBL7873009 | 0.87 | LCK (0.78) | LCK | |
| SCHEMBL7593709 | 0.87 | LCK (0.78) | LCK | |
| SCHEMBL7546015 | 0.86 | LCK (0.61) | LCKIDH1 | |
| SCHEMBL7873023 | 0.85 | LCK (0.49) | LCKIDH1 | |
| SCHEMBL7873020 | 0.85 | LCK (0.49) | LCKIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194152-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1194152-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-04-10 | — | — | EP | disclosed |
| US-6316444-B1 | SRC kinase inhibitor compounds | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |
| WO-2001000214-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |