⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693180 | 0.79 | — | — | |
| SCHEMBL27697692 | 0.68 | — | — | |
| SCHEMBL27927332 | 0.67 | — | — | |
| SCHEMBL25436754 | 0.66 | — | — | |
| SCHEMBL1542058 | 0.66 | — | — | |
| SCHEMBL2761871 | 0.66 | — | — | |
| SCHEMBL28683648 | 0.64 | — | — | |
| SCHEMBL27705308 | 0.64 | — | — | |
| SCHEMBL20337539 | 0.62 | — | — | |
| SCHEMBL20979773 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1150148-C | Reagent and process which are useful for grafting substituted difluoromethyl group onto compound containing at least one electrophilic function | ���ɡ����ʿ˻�ѧ��˾ | 2004-05-19 | — | — | CN | disclosed |
| US-6464895-B2 | ALSO FOR THE PREPARATION OF OXYSULPHIDE-CONTAINING AND FLUORINE-CONTAINING BY REACTING WITH SULFUR DIOXIDE; POLLUTION CONTROL | RHODIA CHIMIE (FR) | 2002-10-15 | — | — | US | disclosed |
| US-20020042542-A1 | REAGENT AND PROCESS WHICH ARE USEFUL FOR GRAFTING A SUBSTITUTED DIFLUOROMETHYL GROUP ONTO A COMPOUND CONTAINING AT LEAST ONE ELECTROPHILIC FUNCTION | RHODIA-CHIMIE (FR) | 2002-04-11 | — | — | US | disclosed |
| US-5756849-A | Process for grafting a substituted difluoromethyl group onto a compound containing an electrophilic functional group | RHONE-POULENC CHIMIE (FR) | 1998-05-26 | — | — | US | disclosed |
| CN-1137508-A | Reagent and process which are useful for grafting substituted difluoromethyl group onto compound containing at least one electrophilic function | RHONE POULENC CHIMIE (FR) | 1996-12-11 | — | — | CN | disclosed |