Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 16/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.54 |
| ▸ | ITGB8 | P26012 | 6/20 | 0.54 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.54 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554383 | 1.00 | ITGAV (0.54) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7594711 | 1.00 | ITGAV (0.54) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7592186 | 0.94 | ITGAV (0.62) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7557493 | 0.94 | ITGAV (0.62) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7594213 | 0.94 | ITGAV (0.62) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7597763 | 0.88 | ITGAV (0.48) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7596273 | 0.88 | ITGAV (0.48) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7560651 | 0.88 | ITGAV (0.48) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7594494 | 0.88 | ITGAV (0.48) | ITGAVITGB3ITGB8ITGB6ITGA5 | |
| SCHEMBL7596992 | 0.88 | ITGAV (0.48) | ITGAVITGB3ITGB8ITGB6ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040111-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999031099-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |