Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026690 | 0.81 | CYP1A2 (0.44) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL10157247 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL2019580 | 0.75 | MAPT (0.49) | ALDH1A1KDM4EGAAHPGDTSHR | |
| SCHEMBL2021969 | 0.75 | CYP1A2 (0.46) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL2718914 | 0.74 | KMT2A (0.50) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL2024770 | 0.74 | CYP1A2 (0.45) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL12877431 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL537851 | 0.73 | PARP1 (0.46) | PARP1 | |
| SCHEMBL30682026 | 0.72 | GLP1R (0.53) | ALDH1A1KDM4ETSHRHSD17B10CYP1A2 | |
| SCHEMBL26617497 | 0.72 | GLP1R (0.53) | ALDH1A1KDM4ETSHRHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538100-B1 | Process for the preparation of fluoro-quinolin-3-carboxylic acid derivatives | AVENTIS PHARMA SA (FR) | 2002-02-06 | — | — | EP | disclosed |
| EP-0641341-B1 | METHOD FOR PREPARING BENZO [b]NAPHTHYRIDINES | RHONE POULENC RORER SA (FR) | 2000-03-01 | — | — | EP | disclosed |
| EP-0693060-B1 | METHOD OF PREPARATION OF 6-FLUORO-2-HALOGEN QUINOLINE | RHONE POULENC RORER SA (FR) | 1998-03-18 | — | — | EP | disclosed |
| EP-0693060-A1 | METHOD OF PREPARATION OF 6-FLUORO-2-HALOGEN QUINOLINE | Aventis Pharma S.A. (FR) | 1996-01-24 | — | — | EP | disclosed |
| EP-0641341-A1 | METHOD FOR PREPARING BENZO b]NAPHTHYRIDINES | LABORATOIRE ROGER BELLON (FR) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994024113-A1 | METHOD OF PREPARATION OF 6-FLUORO-2-HALOGEN QUINOLINE | RHONE-POULENC RORER S.A. (FR) | 1994-10-27 | — | — | WO | disclosed |
| EP-0607329-A1 | NEW DERIVATIVES OF FLUORO-QUINOLINE CARBOXYLIC-3 ACID AND PREPARATION THEREOF | LABORATOIRE ROGER BELLON (FR) | 1994-07-27 | — | — | EP | disclosed |
| EP-0538100-A1 | New fluoro-quinolin-3-carboxylic acid derivatives and their preparation | LABORATOIRE ROGER BELLON (FR) | 1993-04-21 | — | — | EP | disclosed |
| EP-0538101-A1 | Process for the preparation of benzo(b)naphthyridines | LABORATOIRE ROGER BELLON (FR) | 1993-04-21 | — | — | EP | disclosed |
| WO-1993007127-A1 | NEW DERIVATIVES OF FLUORO-QUINOLINE CARBOXYLIC-3 ACID AND PREPARATION THEREOF | LABORATOIRE ROGER BELLON (FR) | 1993-04-15 | — | — | WO | disclosed |
| WO-1993007145-A1 | METHOD FOR PREPARING BENZO[b]NAPHTHYRIDINES | LABORATOIRE ROGER BELLON (FR) | 1993-04-15 | — | — | WO | disclosed |