⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941750 | 1.00 | — | — | |
| SCHEMBL2473684 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL2473687 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL11870535 | 0.76 | — | — | |
| SCHEMBL10954494 | 0.74 | — | — | |
| SCHEMBL10954501 | 0.74 | — | — | |
| SCHEMBL7593191 | 0.74 | — | — | |
| SCHEMBL7593188 | 0.74 | — | — | |
| SCHEMBL7597258 | 0.73 | — | — | |
| SCHEMBL7593173 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663394-B1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL CO (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-5498725-A | Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0663394-A1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-4508660-A | Carbonylation of olefinically unsaturated nitriles and acids using a sulfone solvent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |