SCHEMBL7590924

SCHEMBL7590924

[Li]C1C(CCC)CCCC1CCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
ADRA2A P08913 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
ADRA1A P35348 1/20 0.33
CYP1A2 P05177 1/20 0.32
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7598416 0.93 CA1 (0.45) CA1CA2CA4ADRA2AADRA2B
SCHEMBL7596763 0.89 CA1 (0.42) CA1CA2CA4NOS1NOS2
SCHEMBL7598282 0.86 CA1 (0.43) CA1CA2CA4NOS1NOS2
SCHEMBL7594467 0.85 CYP1A2 (0.44) CA1CA2CA4CYP1A2NOS1
SCHEMBL17063633 0.83 CA1 (0.59) CA1CA2CA4ADRA2AADRA2B
SCHEMBL7595370 0.82
SCHEMBL7598291 0.82 CA1 (0.38) CA1CA2CA4NOS1NOS2
SCHEMBL7592388 0.80 CYP1A2 (0.40) CA1CA2CA4CYP1A2NOS1
SCHEMBL7595347 0.78 CA1 (0.32) CA1CA2CA4
SCHEMBL11591596 0.77 CA1 (0.67) CA1CA2CA4ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894802-B1 Silane compound NIPPON MITSUBISHI OIL CORP (JP) 2002-11-06 EP disclosed
US-6150549-A Silane compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-11-21 US disclosed
EP-0894802-A2 Silane compound NIPPON OIL CO. LTD. (JP) 1999-02-03 EP disclosed