SCHEMBL7590952

SCHEMBL7590952

C=CCC(C(N)=O)C(O)(CC=C)C(N)=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.35
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2185033 0.82 HTT (0.31) HTT
SCHEMBL28430073 0.79 HTT (0.36) HTTGRIK1GRIK2
SCHEMBL7649445 0.77 HTT (0.33) HTT
SCHEMBL28339961 0.77 HTT (0.37) HTT
SCHEMBL6473096 0.75 CPT2 (0.43) GRIK1GRIK2
SCHEMBL6455497 0.72 GRIK1 (0.34) GRIK1GRIK2
SCHEMBL28339959 0.72 CPT2 (0.42) HTTGRIK1GRIK2
SCHEMBL7703170 0.69 GRIK1 (0.32) GRIK1GRIK2
SCHEMBL28284078 0.69 HTT (0.34) HTT
SCHEMBL3373613 0.68 HTT (0.31) HTTGRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1245650-A2 Low foam N,N'-dialkylmalamide wetting agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-10-02 EP claimed
US-6413914-B1 AQUEOUS SOLUTIONS; REDUCING SURFACE TENSION; RENEWABLE-BASED SURFACTANTS AIR PRODUCTS AND CHEMICALS, INC. 2002-07-02 US claimed
EP-1245650-A2 Low foam N,N'-dialkylmalamide wetting agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-10-02 EP disclosed
US-6413914-B1 AQUEOUS SOLUTIONS; REDUCING SURFACE TENSION; RENEWABLE-BASED SURFACTANTS AIR PRODUCTS AND CHEMICALS, INC. 2002-07-02 US disclosed