Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.68 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.68 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | PTGFR | P43088 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586539 | 0.93 | PTGIR (0.79) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7587973 | 0.92 | PTGIR (0.72) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7591007 | 0.92 | PTGIR (0.71) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7584933 | 0.91 | PTGIR (0.66) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7591403 | 0.91 | PTGIR (0.63) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7592326 | 0.91 | PTGIR (0.75) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7583578 | 0.91 | PTGIR (0.62) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7583628 | 0.90 | PTGIR (0.55) | PTGIRPTGER2PTGER4PTGER1PTGER3 | |
| SCHEMBL7172670 | 0.90 | PTGIR (0.66) | PTGIRPTGER2PTGER4NR1I2ESR1 | |
| SCHEMBL7591954 | 0.90 | PTGIR (0.66) | PTGIRPTGER2PTGER4NR1I2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | claimed |