Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 17/20 | 0.63 |
| ▸ | MKNK2 | Q9HBH9 | 16/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025681 | 0.82 | MKNK1 (0.87) | MKNK1MKNK2LCK | |
| SCHEMBL7505860 | 0.82 | MKNK1 (0.72) | MKNK1MKNK2LCKCDK2 | |
| SCHEMBL7593897 | 0.79 | MKNK1 (0.68) | MKNK1MKNK2LCKCDK2 | |
| SCHEMBL7099934 | 0.79 | LCK (0.70) | MKNK1MKNK2LCKCDK2 | |
| SCHEMBL7505494 | 0.79 | MKNK2 (0.67) | MKNK1MKNK2LCK | |
| SCHEMBL7571416 | 0.78 | MKNK2 (0.58) | MKNK1MKNK2LCK | |
| SCHEMBL18803526 | 0.78 | MKNK1 (1.00) | MKNK1MKNK2LCK | |
| SCHEMBL7577466 | 0.78 | MKNK1 (1.00) | MKNK1MKNK2LCK | |
| SCHEMBL18803629 | 0.77 | MKNK1 (1.00) | MKNK1MKNK2LCK | |
| SCHEMBL18803552 | 0.77 | MKNK1 (1.00) | MKNK1MKNK2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |