Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sorbic Acid SCHEMBL7593461 | 1.00 | TSHR (0.42) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| Sorbic Acid SCHEMBL28856833 | 1.00 | TSHR (0.42) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| Sorbic Acid SCHEMBL27558473 | 0.94 | TSHR (0.42) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| Sorbic Acid SCHEMBL13035960 | 0.94 | — | — | |
| Sorbic Acid SCHEMBL4918704 | 0.94 | — | — | |
| Sorbic Acid SCHEMBL1648 | 0.94 | — | — | |
| Sorbic Acid SCHEMBL111656 | 0.94 | TSHR (0.47) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| Sorbic Acid SCHEMBL561904 | 0.94 | — | — | |
| Sorbic Acid SCHEMBL5402804 | 0.94 | — | — | |
| Sorbic Acid SCHEMBL561903 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417795-B | Cellulose acetate sorbate and preparation method and application thereof | 南通醋酸纤维有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-116059681-B | Ultrasonic control method and system for controlling crystallization nucleation | 福建省龙德新能源有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116059681-A | Ultrasonic control method and system for controlling crystallization nucleation | 福建省龙德新能源有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115845428-B | Ultrasonic device for inducing crystallization of hexafluorophosphoric acid and control method thereof | 福建省龙德新能源有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-107417795-B | Cellulose acetate sorbate and preparation method and application thereof | 南通醋酸纤维有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-107417795-B | Cellulose acetate sorbate and preparation method and application thereof | 南通醋酸纤维有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-107417795-B | Cellulose acetate sorbate and preparation method and application thereof | 南通醋酸纤维有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-107417795-A | A kind of antibiotic property cellulose acetate and its preparation method and application | 南通醋酸纤维有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-6470705-B2 | Disposable ice pack | BRIDE-FLYNN KELLY L (US) | 2002-10-29 | — | — | US | disclosed |
| US-20020073731-A1 | Disposable ice pack | BRIDE-FLYNN KELLY L (US) | 2002-06-20 | — | — | US | disclosed |
| US-5128329-A | Fenitrothion, sorbitan monooleate, xanthan gum | SUMITOMO CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |