Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA7 | P43166 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27494473 | 0.84 | NPC1 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7595512 | 0.84 | TSHR (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30784110 | 0.84 | NPC1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1928503 | 0.84 | NPC1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5841557 | 0.83 | NPC1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4640072 | 0.82 | TSHR (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17707767 | 0.81 | NPC1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29003949 | 0.81 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29199121 | 0.79 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4641202 | 0.78 | SCN1A (0.36) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855400-B1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL IND LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5880309-A | DIALKYL DIALKOXYCARBONYLPHENYL PHOSPHONATES USEFUL AS RESIN MODIFIERS PRODUCED AT HIGH YIELD AND LOW COST BY HEATING A TRIALKYL PHOSPHITE AND A DIALKOXYCARBONYLPHENYL HALIDE IN THE PRESENCE OF A PALLADIUM OR NICKEL CATALYST AND HYDROLYZING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0855400-A1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |