Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.30 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555066 | 0.91 | PNP (0.40) | PNPALDH1A1TK1KDM4ETDP1 | |
| SCHEMBL6275156 | 0.82 | PNP (0.42) | PNPALDH1A1TK1KDM4ETDP1 | |
| SCHEMBL28297130 | 0.79 | PNP (0.42) | PNPALDH1A1TK1KDM4ETDP1 | |
| SCHEMBL8884689 | 0.76 | PNP (0.40) | PNPALDH1A1KDM4ETDP1 | |
| SCHEMBL7221073 | 0.75 | PNP (0.38) | PNPALDH1A1KDM4ETDP1 | |
| SCHEMBL27586845 | 0.71 | PNP (0.53) | PNPALDH1A1HPRT1TK1 | |
| SCHEMBL28383481 | 0.70 | PNP (0.38) | PNPALDH1A1KDM4ETDP1 | |
| SCHEMBL133948 | 0.69 | PNP (0.41) | PNPALDH1A1TK1KDM4ETDP1 | |
| SCHEMBL618978 | 0.69 | PNP (0.44) | PNPALDH1A1TK1KDM4ETDP1 | |
| SCHEMBL2837687 | 0.69 | PNP (0.41) | PNPALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653065-B1 | SEPARATION METHOD | MARCONI OPTICAL COMPONENTS LTD (GB) | 2002-10-30 | — | — | EP | claimed |
| EP-0660935-B1 | IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS | MARCONI GEC LTD (GB) | 2000-05-24 | — | — | EP | claimed |
| US-5723304-A | Immunological detection using two detectable labels | GEC-MARCONI LIMITED (GB) | 1998-03-03 | — | — | US | claimed |
| EP-0660935-A1 | IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS | GEC-MARCONI LIMITED (GB) | 1995-07-05 | — | — | EP | claimed |
| EP-0653065-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1995-05-17 | — | — | EP | claimed |
| WO-1994003811-A1 | IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS | GEC-MARCONI LIMITED (GB) | 1994-02-17 | — | — | WO | claimed |
| WO-1994003807-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1994-02-17 | — | — | WO | claimed |
| EP-0653065-B1 | SEPARATION METHOD | MARCONI OPTICAL COMPONENTS LTD (GB) | 2002-10-30 | — | — | EP | disclosed |
| EP-0660935-B1 | IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS | MARCONI GEC LTD (GB) | 2000-05-24 | — | — | EP | disclosed |
| US-5723304-A | Immunological detection using two detectable labels | GEC-MARCONI LIMITED (GB) | 1998-03-03 | — | — | US | disclosed |
| EP-0660935-A1 | IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS | GEC-MARCONI LIMITED (GB) | 1995-07-05 | — | — | EP | disclosed |
| EP-0653065-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994012878-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |
| WO-1994003807-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |
| WO-1994003811-A1 | IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS | GEC-MARCONI LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |