Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911384 | 0.85 | SYK (0.70) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL20299917 | 0.84 | SYK (0.59) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL20299921 | 0.84 | SYK (0.59) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL16824022 | 0.84 | SYK (0.61) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL6936043 | 0.84 | SYK (0.61) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL16824023 | 0.84 | SYK (0.61) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL19812740 | 0.84 | SYK (0.61) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL7216424 | 0.84 | SYK (0.61) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL18143207 | 0.84 | SYK (0.61) | SYKPPARAATMCTSLMAPT | |
| SCHEMBL21125395 | 0.83 | SYK (0.60) | SYKPPARAATMCTSLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002099388-A2 | BENZODIAZEPINE BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2002-12-12 | — | — | WO | disclosed |