Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128266 | 1.00 | PTPN1 (0.51) | PTPN1PTPN11CHRNA7HTR3EHTR3B | |
| SCHEMBL7125035 | 0.90 | CHRNA7 (0.52) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7593274 | 0.90 | CHRNA7 (0.52) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7226655 | 0.89 | CHRNA7 (0.49) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7168431 | 0.89 | CHRNA7 (0.49) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7113670 | 0.88 | CHRNA7 (0.56) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7593090 | 0.88 | CHRNA7 (0.48) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7122009 | 0.88 | CHRNA7 (0.48) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7118956 | 0.88 | CHRNA7 (0.53) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7124472 | 0.88 | CHRNA7 (0.64) | CHRNA7HTR3EHTR3BALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002015662-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |
| WO-2002015662-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |