Acesulfame

Acesulfame

SCHEMBL7594675

CC1=CC(=O)NS(=O)(=O)O1.CC1=CC(=O)NS(=O)(=O)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 7/20 1.00
KMT2A Q03164 1/20 0.41
CA12 O43570 6/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acesulfame SCHEMBL3551 1.00 CA9 (1.00) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL38654964 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL38656077 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL38655123 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL17350249 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL3126570 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL7568032 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL328775 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL17766790 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2
Acesulfame SCHEMBL29471225 0.98 CA9 (0.96) CA9KMT2ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1206466-A1 ALKOXY SUBSTITUTED BENZIMIDAZOLE COMPOUNDS, PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME aaiPharma Inc. (US) 2002-05-22 EP disclosed
WO-2001014367-A1 ALKOXY SUBSTITUTED BENZIMIDAZOLE COMPOUNDS, PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME APPLIED ANALYTICAL INDUSTRIES, INC. (US) 2001-03-01 WO disclosed