SCHEMBL7594932

SCHEMBL7594932

O=C(Cl)OCC1c2ccccc2-c2cccc(Cl)c21

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.51
FABP7 O15540 2/20 0.51
EPHX2 P34913 1/20 0.43
KMT2A Q03164 2/20 0.43
PPIA P62937 3/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HTR7 P34969 2/20 0.36
HTR2B P41595 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HTR2A P28223 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27547 0.85 KMT2A (0.55) FABP5FABP7EPHX2KMT2ACA1
SCHEMBL29349891 0.85 KMT2A (0.55) FABP5FABP7EPHX2KMT2ACA1
SCHEMBL9449543 0.84 EPHX2 (0.42) FABP5FABP7EPHX2KMT2ACA1
Hydrochloric Acid SCHEMBL810434 0.83 KMT2A (0.54) FABP5FABP7EPHX2KMT2ACA1
Ammonia Solution, Strong SCHEMBL27794450 0.83 KMT2A (0.54) FABP5FABP7EPHX2KMT2ACA1
Acetonitrile SCHEMBL29013970 0.77 KMT2A (0.48) FABP5FABP7EPHX2KMT2ACA1
Ortho-Phthalaldehyde SCHEMBL29008730 0.75 KMT2A (0.47) FABP5FABP7EPHX2KMT2ACA1
SCHEMBL8101665 0.75 FABP5 (0.49) FABP5FABP7EPHX2KMT2ACA1
SCHEMBL8987625 0.73 EPHX2 (0.42) FABP5FABP7EPHX2KMT2ACA1
SCHEMBL24108959 0.73 EPHX2 (0.45) FABP5FABP7EPHX2KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1255567-A1 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES Drug Innovation & Design, Inc. (US) 2002-11-13 EP disclosed
WO-2001036003-A2 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES DRUG INNOVATION & DESIGN, INC. (US) 2001-05-25 WO disclosed