Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | TARS1 | P26639 | 3/20 | 0.35 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NAT1 | P18440 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935659 | 0.82 | CDK8 (0.49) | CDK8TRIM24TRIM33UNGAXL | |
| SCHEMBL4081950 | 0.82 | CDK8 (0.49) | CDK8TRIM24TRIM33UNGAXL | |
| 3-Hydroxybenzaldehyde SCHEMBL3218537 | 0.77 | KDM4E (0.48) | TRIM24TRIM33SLC7A5UNG | |
| Valine SCHEMBL8645296 | 0.76 | SLC7A5 (0.37) | SLC7A5 | |
| Valine SCHEMBL1357700 | 0.73 | SLC7A5 (0.56) | SLC7A5UNG | |
| SCHEMBL21946228 | 0.72 | GRIA2 (0.59) | SLC7A5 | |
| Hydrochloric Acid SCHEMBL20502561 | 0.71 | GRIA2 (0.58) | SLC7A5 | |
| Hydrochloric Acid SCHEMBL20502559 | 0.71 | GRIA2 (0.58) | SLC7A5 | |
| Hydrochloric Acid SCHEMBL21879188 | 0.71 | GRIA2 (0.58) | SLC7A5 | |
| Hydrochloric Acid SCHEMBL21879189 | 0.71 | GRIA2 (0.58) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915853-B1 | SUBSTITUTED 3-PHENYL PYRAZOLES | BASF AG (DE) | 2002-11-06 | — | — | EP | disclosed |
| US-6197973-B1 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| EP-0915853-A1 | SUBSTITUTED 3-PHENYL PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005649-A1 | SUBSTITUTED 3-PHENYL PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-12 | — | — | WO | disclosed |