SCHEMBL7595430

SCHEMBL7595430

CCCCC1CCCC(CC)C1[SiH3]

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
DPP4 P27487 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7597543 0.94 CYP1A2 (0.44) CYP1A2NOS1NOS2DPP4CA1
SCHEMBL7593643 0.91 CYP1A2 (0.38) CYP1A2NOS1NOS2DPP4CHRNB2
SCHEMBL7595891 0.87 CA1 (0.45) NOS1NOS2CA1CA2CA4
SCHEMBL7597647 0.84 CYP1A2 (0.42) CYP1A2NOS1NOS2DPP4CA1
SCHEMBL7599096 0.84 CA1 (0.32) CA1CA2CA4
SCHEMBL7599375 0.82 CYP1A2 (0.39) CYP1A2NOS1NOS2DPP4CA1
SCHEMBL7594292 0.80 CA1 (0.50) CYP1A2NOS1NOS2CA1CA2
SCHEMBL7598500 0.78 CYP1A2 (0.43) CYP1A2NOS1NOS2DPP4CA1
SCHEMBL7599370 0.78 CA1 (0.38) NOS1NOS2CA1CA2CA4
SCHEMBL8675580 0.78 CYP1A2 (0.52) CYP1A2NOS1NOS2DPP4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894802-B1 Silane compound NIPPON MITSUBISHI OIL CORP (JP) 2002-11-06 EP disclosed
US-6150549-A Silane compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-11-21 US disclosed
EP-0894802-A2 Silane compound NIPPON OIL CO. LTD. (JP) 1999-02-03 EP disclosed