Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.67 |
| ▸ | NPY1R | P25929 | 9/20 | 0.67 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.67 |
| ▸ | NPY2R | P49146 | 5/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595615 | 1.00 | NPY4R (0.67) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL30988894 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30900195 | 0.91 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30900117 | 0.91 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL9419207 | 0.90 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL9419213 | 0.90 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL13449160 | 0.90 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30512596 | 0.89 | NPY4R (0.67) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL29689385 | 0.88 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL6473543 | 0.88 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438600-B2 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6156555-A | Method of preparing an enzyme participating in C-terminal amidation | SHISEIDO COMPANY LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0666318-B1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO CO LTD (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-5871995-A | Purified enzymes participating in C-terminal amidation | SHISEIDO COMPANY, LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0884389-A1 | Enzyme participating in C-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0438600-B1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0666318-A1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0438600-A1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO COMPANY LIMITED (JP) | 1991-07-31 | — | — | EP | disclosed |