Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591127 | 0.92 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL7590132 | 0.85 | PTGDR2 (0.43) | POLBTDP1PTGDR2TBXA2RPTGDR | |
| SCHEMBL7590134 | 0.79 | PTGDR2 (0.49) | POLBTDP1PTGDR2TBXA2RPTGDR | |
| SCHEMBL9232548 | 0.79 | PTGDR2 (0.49) | TDP1PTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL7591129 | 0.79 | PTGDR2 (0.49) | TDP1PTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL7586678 | 0.73 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL3127128 | 0.71 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL832665 | 0.69 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL832313 | 0.69 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL832314 | 0.69 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728743-B1 | 3-Amino-tetrahydrocarbazol propanoic acid esters | BAYER AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| EP-0728743-A1 | 3-Amino-tetrahydrocarbazol propanoic acid esters | BAYER AG (DE) | 1996-08-28 | — | — | EP | disclosed |