Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598864 | 0.88 | HSD17B10 (0.53) | MMEHSD17B10MMP1MMP3ECE1 | |
| SCHEMBL7598936 | 0.85 | HSD17B10 (0.49) | MMEHSD17B10MAPTMMP1MMP3 | |
| SCHEMBL7598874 | 0.82 | HSD17B10 (0.62) | MMEHSD17B10MMP1MMP3ECE1 | |
| SCHEMBL7597454 | 0.82 | HSD17B10 (0.47) | MMEHSD17B10MMP1MMP3ECE1 | |
| SCHEMBL7598928 | 0.82 | HSD17B10 (0.47) | HSD17B10MMP1MMP3 | |
| SCHEMBL7600370 | 0.79 | HSD17B10 (0.46) | MMEHSD17B10MMP1MMP3ECE1 | |
| SCHEMBL7596590 | 0.79 | HSD17B10 (0.49) | MMEHSD17B10MMP1MMP3ECE1 | |
| SCHEMBL7602529 | 0.79 | HSD17B10 (0.47) | HSD17B10MMP1MMP3 | |
| SCHEMBL7598954 | 0.76 | HSD17B10 (0.54) | HSD17B10MMP1MMP3 | |
| SCHEMBL7605750 | 0.76 | HSD17B10 (0.56) | HSD17B10MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |